MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.

J Exp Med · 2013 · PMC3646497 · PMID 23569328

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clearly significantlyP < 0.001actually significant

Overall, the MHC II tetramer-positive CD4 + T cells in acute IM displayed an activated phenotype that was clearly significantly different from that of the total CD4 + T cell populations (P < 0.001 or P < 0.0001 by unpaired Student’s t test with Welch’s correction for all markers).

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