Barely Significant
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The majority of primate-specific regulatory sequences are derived from transposable elements.

PLoS Genet · 2013 · PMC3649963 · PMID 23675311

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The sentences

highly significantp <1.0E-100actually significant
This corresponds to a 20-fold enrichment and is highly significant ( p <1.0E-100).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.