Also, there may be significant unmeasured confounding factors we were unable to control for in the subgroup comparison of cohorts, and we used non-standardized measurements to assess clinical outcomes, including hypoglycemia, which relied on patient recall and self-reporting of episodes that did not have standardized diagnoses.
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Treatment outcomes after initiation of exenatide twice daily or insulin in clinical practice: 12-month results from CHOICE in six European countries.
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