Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study.

PLoS One · 2013 · PMC3655963 · PMID 23696797

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of borderline significanceno p-value reported

Among women with the most Native American ancestry, MMP1 and MMP3 were of borderline significance (p artp = 0.07 and 0.06 respectively) whereas MMP9 was statistically significant among this group of women (p artp = 0.024).

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borderline significantno p-value reported

Significant pathway genes using the ARTP were MMP1 for all women (p artp = 0.02) and MMP9 for women with the most NA ancestry (p artp = 0.024); MMP2 was borderline significant overall (p artp = 0.06) and MMP1 and MMP3 were borderline significant for women with the most NA ancestry (p artp = 0.07 and 0.06 respectively).

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highly significantno p-value reported

The pathway was highly significant with survival (p artp = 0.0041) with MMP2 having the strongest gene association (p artp = 0.0007).

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