Bone mineralization and age-based bone growth can be checked and related to levels of GH/IGF-1.[ 3 ] GH deficiency affects body composition, physical performance and substrate metabolism and its replacement attenuates these effects; short-term and long-term effects of replacement may be significant.[ 4 ] It is important to remember the physiological effects of deficiency of the hormones in the peri-operative period.
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Laparoscopic appendicectomy in a child with multiple pituitary hormone deficiency.
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