Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.

PLoS One · 2013 · PMC3659082 · PMID 23700438

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highly significantno p-value reported

Although the impairment is not as severe as in the daf-2(e1391) strain, the data are highly significant.

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