Barely Significant
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Hnf-1β transcription factor is an early hif-1α-independent marker of epithelial hypoxia and controls renal repair.

PLoS One · 2013 · PMC3660442 · PMID 23704921

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highly significantno p-value reported
This down regulation became highly significant at 72 hours of hypoxia.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.