Evolution of smooth tubercle Bacilli PE and PE_PGRS genes: evidence for a prominent role of recombination and imprint of positive selection.

Evidence for recombination was supported by highly significant PHI test values ( P = 3.17E−4; Fig. 2 ).

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Only for PE4 and PE_PGRS62, was the likelihood ratio test close to significance for both models comparisons M1a vs M2a and M8a vs M8 (data not shown), and a few amino acid sites were identified under positive selection with Bayes empirical Bayes (BEB) analysis ( Table 5 ).

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