highly significantp = 6.69×10 −5
We therefore re-analyzed the genome-wide expression profiles (Gene Expression Omnibus accession number GSE21260 ) of several different uninfected KC cultures and hrHPV+ KC cultures reported previously [10] by Ingenuity Pathways Analysis (IPA) and found a highly significant enrichment of genes belonging to the protein ubiquitination pathway ( Table S1 ; p = 6.69×10 −5 ).