Sixty years of genome biology.

Genome Biol · 2013 · PMC3663092 · PMID 23651518

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incredibly significantno p-value reported

Determining the structure of DNA in 1953 was incredibly significant for determining the molecular framework for so many aspects of biology, including the frameworks for replication, transcription, inheritance, mutation and evolution, to name but a few.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.