Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?

PLoS One · 2013 · PMC3664616 · PMID 23724048

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an increasing trendno p-value reported

Previously, we found an increasing trend over time in plasma HIV-1 RNA concentration at set-point, i.e., 9 to 27 months after HIV-1 seroconversion and an accompanying decreasing trend of CD4 cell count measured at viral set-point [3] .

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