Comparative effectiveness of novel oral anticoagulants for atrial fibrillation: evidence from pair-wise and warfarin-controlled network meta-analyses.

HSR Proc Intensive Care Cardiovasc Anesth · 2013 · PMC3670724 · PMID 23734288

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a favorable trendno p-value reported

After a weighted average follow-up of 23 months, novel oral anticoagulants were associated with significant reductions in the risk of stroke or systemic embolism (OR=0.81 [0.71-0.92], I 2 =23%) all cause death (OR=0.88 [0.82-0.95], I 2 =0%), in comparison to warfarin, with a favorable trend for major bleeding (OR=0.83 [0.68-1.02], I 2 =73%).

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