Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model.

In particular, we found a highly significant positive correlation between disease and the Magenta (comprised of 576 genes) module eigengene ( r = 0.67, P <2 × 10 -7 ), the Brown (2,502 genes) module eigengene ( r = 0.6, P <6 × 10 -6 ), the Light-Cyan (349 genes) module eigengene ( r = 0.42, P <0.002), and the Grey60 (based on 216 genes) module eigengene ( r = 0.47, P <8 × 10 -4 ).

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