Cholesterol accelerates the binding of Alzheimer's β-amyloid peptide to ganglioside GM1 through a universal hydrogen-bond-dependent sterol tuning of glycolipid conformation.

Front Physiol · 2013 · PMC3677124 · PMID 23772214

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highly significantno p-value reported

However, the involvement of the glycosidic bond (or alternatively the C 2 –OH of the first sugar) in these lipid–lipid hydrogen-bond-driven interactions is highly significant.

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