GO analysis of the Leydig enriched transcripts (7-fold or higher) revealed highly significant molecular function and biological process categories related to steroidogenesis ( Table S5 ), such as lipid, alcohol, cellular ketone and organic acid metabolic processes, oxidoreductase activity, steroid dehydrogenase activity and steroid and coenzyme binding, confirming the highly specialized nature of this cell type in the testis.
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RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo.
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