The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies.

PLoS One · 2013 · PMC3681965 · PMID 23785471

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantP <0.0001actually significant

The results presented in Figure 1B–C clearly support our hypothesis: antibody treatment did not significantly impact tumor growth in B16.F10 challenged mice ( P = 0.1850); whereas the effect on B16.F10-GP challenged mice were highly significant ( P <0.0001).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.