SynDIG1 promotes excitatory synaptogenesis independent of AMPA receptor trafficking and biophysical regulation.

PLoS One · 2013 · PMC3681968 · PMID 23785483

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highly significantno p-value reported

Coexpression of the AMPAR auxiliary subunit TARP γ-2 with GluA2(Q)–the unedited form of the receptor that generates much larger currents–in HEK cells results in a highly significant increase in the response to kainate versus glutamate application, in agreement with previous findings that TARP association greatly increases kainate sensitivity of AMPARs [8] .

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