Samples from leprosy patients showed down-regulation of CCL2, CCL3, CCL4 (p<0.05), while IL1β and SOD2 were borderline significant (p<0.1), confirming a repression of these genes by M. leprae ex vivo , as was observed in vitro in THP-1 ( Figure 2 ).
← all excerpts
Gene expression profiling specifies chemokine, mitochondrial and lipid metabolism signatures in leprosy.
2
0.1000
0.1000
The sentences
Two-tailed levels of significance less than or equal to 0.01, 0.05 and 0.1 were considered as “highly significant”, “significant” and “suggestive”, respectively.