highly significantP < 0.005
8 point to the mutations R352C, L361C, E363C, and V365C as causing a highly significant (P < 0.005) increase in the channel deactivation time t off .
8 point to the mutations R352C, L361C, E363C, and V365C as causing a highly significant (P < 0.005) increase in the channel deactivation time t off .