Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin.

Transl Psychiatry · 2013 · PMC3693404 · PMID 23756378

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP <2.2 × 10 −16actually significant

The difference in variance across all probes between affected and unaffected twins was highly significant ( P <2.2 × 10 −16 ), with 52.4% of probes having higher variance in cases (binomial P -value<2.2 × 10 −16 ).

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