highly significantp<0.01
Length and brain areas were measured using Image-Pro Plus 3D Suite software revealed highly significant reduction in the cortical plate (CP) length at level 2 (31%, p<0.01), level 3 (47%, p<0.01), level 4 (38%, p<0.01) and level 5 (46%, p<0.01) in Ran−/− pups compared to littermate WT controls ( Fig. 4A ) .