an increasing trendP = 0.006
Allelic discrimination of 73 sarcoidosis patients and 215 healthy individuals showed that the frequency of the 796A-type allele is significantly higher in sarcoidosis patients and the odds ratios (ORs) are significantly elevated in NOD1-796G/A and 796A/A genotypes (OR (95% CI) = 2.250 (1.084, 4.670) and 3.243 (1.402, 7.502), resp.) as compared to the G/G genotype, showing an increasing trend across the 3 genotypes ( P = 0.006 for trend).