By 2‐factor RM‐ANOVA, R‐138727, GPIIb‐IIIa antagonists, and the interaction between R‐138727 and GPIIb‐IIIa antagonists were highly significant for the collagen plus ADP–stimulated percentage of monocyte–platelet aggregates and the platelet fluorescence in monocyte–platelet aggregates (Table).
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P2Y12 receptor blockade augments glycoprotein IIb-IIIa antagonist inhibition of platelet activation, aggregation, and procoagulant activity.
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