Genetic polymorphisms of the CASP8 gene promoter may not be associated with colorectal cancer in Han Chinese from southwest China.

Cancerous and paracancerous normal tissues from patients at different stages of cancer development and progression had a similar level of CASP8 mRNA expression ( Figure 4 ), although cancerous tissues from patients at T4 stage had a marginally significant higher mRNA expression than paired paracancerous normal tissues ( P = 0.045; Figure 4c ).

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