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Seasonal and temporal variation in release of antibiotics in hospital wastewater: estimation using continuous and grab sampling.

PLoS One · 2013 · PMC3704537 · PMID 23861936

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an increasing trendno p-value reported
For the same time frame, the grab sampling method showed an increasing trend from summer to the rainy season to winter.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.