It is possible, however, that highly significant miRSNPs exist that were not identified in our study because a) they were not pre-selected for evaluation (i.e. they do not reside in a binding site involving miRNAs or genes with known relevance to EOC, or they reside in regions other than the 3′UTR 3 , 4 ) and/or b) they were very rare and could not be designed or detected with our genotyping platform and sample size, respectively.
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Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
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