HIV-1 diversity, drug-resistant mutations, and viral evolution among high-risk individuals in phase II HIV vaccine trial sites in southern China.

The difference between the two groups was highly significant (p<0.001, Student’s test, two-tailed, with Microsoft Excel) in terms of the evolution of the sequences, meaning that recent Guangxi CRF08_BC strains were more evolutionarily different from each other, suggesting perhaps that these strains undergo adaption that allows them to infect people in this locality.

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