Three Tibetan high-altitude selection candidates are also highly significant in DU Mongolians, including the hypoxia inducible pathway gene EPAS1 [20] – [22] , [24] – [27] ( Figure 4 ); the PKLR gene [20] – [22] , which encodes liver- and erythrocyte-expressed pyruvate kinase; and the cytochrome P450 family member CYP2E1 [20] .
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Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.
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