Barely Significant
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The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.

PLoS Genet · 2013 · PMC3715428 · PMID 23874226

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The sentences

highly significantp<0.0001actually significant
The changes in expression between ab and scrib − + ab samples were also all highly significant (p<0.0001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.