A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal.

Oncotarget · 2013 · PMC3717308 · PMID 23531874

Europe PMC DOI

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closest p · 1.4× alpha

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The sentences

a trend toward significancep=0.07so close (0.05 < p ≤ 0.1)

Comparing OSI-906 plus non-targeted siRNA to OSI-906 plus IGF-1R siRNA (Figure 5 compare bar D and F) shows that IGF-1R siRNA is significantly better than non-targeted siRNA when combined with OSI-906 in HEK293 cells at 72 hours (p<0.05) and MCF7 at 96 hours (p<0.001), and shows a trend toward significance in MCF7 cells at 72 hours (p=0.07).

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