Barely Significant
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The V471A polymorphism in autophagy-related gene ATG7 modifies age at onset specifically in Italian Huntington disease patients.

PLoS One · 2013 · PMC3718802 · PMID 23894380

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highly significantP<0.0001actually significant
As this factor showed a highly significant effect on the HD AAO (P<0.0001), we split the HD patients of the EHDN REGISTRY cohort as well as the 1 st European HD cohort by ancestry and analysed the impact of the ATG7 V471A polymorphism in these single groups.

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