Relation of HLA class I and II supertypes with spontaneous clearance of hepatitis C virus.

However, three other supertypes were borderline significant using FDR-adjusted q values ( q < 0.10), including the DR8 supertype (PR: 1.84; 95% CI: 1.19–2.85; p =0.007; q = 0.080; p permutation = 0.917) described by Lund et al., 15 the DR1*01 supertype (PR: 1.70; 95% CI: 1.14–2.56; p =0.01; q = 0.098; p permutation = 0.336) described by Nielsen et al., 16 a

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Table 1 shows the individual HLA alleles that comprise the four supertypes that remained significant or of borderline significance after adjustment for multiple tests.

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