Barely Significant
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A review of the gastrointestinal therapeutic system (GITS) formulation and its effectiveness in the delivery of antihypertensive drug treatment (focus on nifedipine GITS).

Integr Blood Press Control · 2013 · PMC3724274 · PMID 23901292

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highly significantP < 0.001actually significant
In the first reported comparative study of nifedipine GITS, a hydrophilic matrix tablet of nifedipine based on hydroxypropyl methylcellulose as the gel-forming agent was shown to have a highly significant ( P < 0.001) increase in AUC and C max with food relative to the fasting state after a single dose. 21 Similar discrepancies have been seen in other comparative studies.

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