Attention enhances synaptic efficacy and the signal-to-noise ratio in neural circuits.

When we compared thalamocortical synaptic efficacy (percent of presynaptic shocks that evoked a postsynaptic spike) as a function of attention, we observed a highly significant increase in synaptic efficacy when covert spatial attention was directed toward the receptive fields of recorded TCR neurons compared to when attention was directed away from TCR receptive fields (p = 1×10 −7 ; Fig. 2d ).

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