Experimental evolution of protein-protein interaction networks.

Biochem J · 2013 · PMC3727214 · PMID 23849056

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an increasing trendno p-value reported

A variety of ancestral EF-Tu proteins have been resurrected through ASR, and have been shown to demonstrate an increasing trend in their melting temperatures as one travels further back in evolutionary time, in agreement with the Earth's larger paleotemperature trend [ 81 ].

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