Structure-based mechanism for early PLP-mediated steps of rabbit cytosolic serine hydroxymethyltransferase reaction.

Biomed Res Int · 2013 · PMC3728543 · PMID 23956983

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a decreasing trendno p-value reported

When L-serine was used as substrate, k off ⁡ values showed a decreasing trend as pH was increased and ranged from 10.3 to 3.1 s −1 for the T254A mutant form and from 39 to 23 s −1 for T254C.

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