Fungal genes in context: genome architecture reflects regulatory complexity and function.

Orthologs with nonconserved small UIR were still significantly different for many experiments (e.g., by mean expression for 73 conditions) and hierarchical clustering of conditions showed they often responded similarly to small, conserved length UIR genes, suggesting related gene function. For a number of experiments, modest but highly significant correlation between gene expression and intergenic size was apparent without regard to conservation of genes or UIR size across species (e.g., maximum Spearman’s ρ for A. nidulans and A. fumigatus vegetative growth data sets of 0.33 and 0.32).

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