There was a highly significant correlation between the CYP17A1 expression and percentage of ZF cells, estimated by an adrenal pathologist blind to the biochemical data; CYP17A1 encodes the enzyme which converts aldosterone precursors to cortisol precursors, and is normally considered absent from ZG. 14 So Choi's paper suggested two immediate questions.
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Platt versus Pickering: what molecular insight to primary hyperaldosteronism tells us about hypertension.
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