Specific inhibition of tumor cells by oncogenic EGFR specific silencing by RNA interference.

PLoS One · 2013 · PMC3738543 · PMID 23951344

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an increasing trendno p-value reported

Gefitinib treatment worked for the suppression of tumor growth, whereas intestinal apoptosis was significantly frequent in the mice treated with a high dose of gefitinib (100 mg/kg b.w.), and also the treated mice exhibited an increasing trend in the level of plasma alkaline phosphatase, GOT, GPT and (total-, direct- and indirect-) bilirubin.

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