7 , 8 In one of these studies, a marginal significance for frequency of the APOE ε4 and rs1080985 G allele was found, but an independent effect of APOE ε4 on response to donepezil was not found. 8 In our study, APOE ε4 was not significantly associated with the therapeutic response to donepezil.
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Influence of rs1080985 single nucleotide polymorphism of the CYP2D6 gene on response to treatment with donepezil in patients with alzheimer's disease.
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