Effect of doxorubicin/pluronic SP1049C on tumorigenicity, aggressiveness, DNA methylation and stem cell markers in murine leukemia.

PLoS One · 2013 · PMC3747131 · PMID 23977261

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may be significantno p-value reported

In this case some cancer cells in the tumor may have different tumorigenic potential and, in contrary to CSC model, the number of tumor initiating cells (TIC) may be significant (up to 25%), but the tumors are not hierarchically organized [17] , [18] .

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