Barely Significant
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The diverse distribution of risk factors between breast cancer subtypes of ER, PR and HER2: a 10-year retrospective multi-center study in China.

PLoS One · 2013 · PMC3748061 · PMID 23977244

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an increasing trendno p-value reported
The age-standardized rate of incidence was 21.6/10 5 and had an increasing trend which suggested the serious challenge [1] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.