Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells.

Other high-scoring (highly significant) categories under Top Biologic Functions include “Cancer” under Diseases and Disorders ( Figure 6B ), “Cell Cycle”, “Cell Death”, and “Cell Growth and Proliferation” under Molecular and Cellular Functions ( Figure 6C ), and “Tumor Development” and “Tissue Development” under Physiological Systems Development and Function ( Figure 6D ).

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