Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.

Biochem J · 2013 · PMC3749867 · PMID 23758345

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may not be significantno p-value reported

Our studies have not identified alternative substrates or mechanisms of substrate presentation to suggest that in vivo the differences may not be significant.

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