Barely Significant
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Study protocol for the randomised controlled trial: antiglucocorticoid augmentation of anti-Depressants in Depression (The ADD Study).

BMC Psychiatry · 2013 · PMC3750720 · PMID 23914988

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highly significantno p-value reported
Previous data shows that metyrapone administration is associated with highly significant increases in 11-deoxycortisol [ 33 , 82 ] due to its effect of blocking 11β-hydroxylase.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.