Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal.

Am J Trop Med Hyg · 2013 · PMC3752812 · PMID 23589534

Europe PMC DOI

hedged sentences

0.1500

closest p · 3.0× alpha

0.1700

boldest claim

The sentences

a weak trendP = 0.15not close (p > 0.1)

A weak trend for decreasing prevalence of quadruple mutants (triple Pfdhfr + Pfdhps 437G) was noted in both groups ( P = 0.15 and P = 0.34).

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a small trendP = 0.17not close (p > 0.1)

Regarding the triple mutant Pfdhfr haplotype (C IRN ), there was a small trend for an increase in prevalence in the control group from 52.1% (37 of 71) in 2009 to 64.3% (36 of 56) in 2010 (χ 2 = 1.90, P = 0.17), whereas in the IPT group, it was significant, from 40.6% (28 of 69) in 2009 to 64.6% (42 of 65) in 2010 was observed (χ 2 = 7.75, P = 0.005).

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