Altered levels of sphingosine and sphinganine in psoriatic epidermis.

Ann Dermatol · 2013 · PMC3756197 · PMID 24003275

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highly significantno p-value reported

Although there was no altered ceramide synthase and ceramidase, there was a highly significant positive correlation between the % change of ceramidase, the degradative enzyme of ceramide into sphingosine, and the Psoriasis Area Severity Index (PASI) score.

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