The individualized genetic barrier predicts treatment response in a large cohort of HIV-1 infected patients.

PLoS Comput Biol · 2013 · PMC3757085 · PMID 24009493

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a pronounced trendno p-value reported

Among PIs, a pronounced trend was that boosting with RTV increased the odds of successful treatment.

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failed to reach significanceno p-value reported

For example, adherence is a well-known predictor of treatment success [50] , [51] , but it failed to reach significance in the multivariate model, most likely due to lack of adherence data for about 45% of the patients.

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