Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment.

Neuroimage Clin · 2012 · PMC3757723 · PMID 24179750

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highly significantno p-value reported

In the MCI group, regional brain volumes showed strongest and most highly significant associations with homocysteine levels in our earlier work ( Rajagopalan et al., 2011 ).

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