Gender, sex hormones and pulmonary hypertension.

Pulm Circ · 2013 · PMC3757824 · PMID 24015330

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a nonsignificant trendno p-value reported

BMPR2 R899X mutant treated with 2-ME alone had a nonsignificant trend toward worse PVR than mutant mice treated with vehicle; those treated with 2-ME in addition to 16α-OHE 1 had a nonsignificant trend toward improvement compared with 16α-OHE 1 alone (although still worse than mutant mice with vehicle).

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